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Excipients
Functional Ingredients
The expectations on excipients have grown over the last years. No longer seen as mere fillers and binders, pharma is now looking toward excipients that add value to their end product and are multifunctional. The most exciting trend in excipients is ... more
Chemical Distribution: Three Attractive Markets
Desirable Markets - The area of life sciences covers nutrition, health and wellness of animals and humans. As such, several segments of this industry are attractive to chemical distributors, in particular pharmaceuticals, food, and cosmetics. Chemical distributors supply these segments with ingredients, additives, excipients and processing aids. From a producer's perspective, the attractiveness of these segments is typically defined by relevant market size, growth, profitability and sustainability. more
Intensive Cooperation
Wake-up Call - Infant formula laced with melamine, heparin tainted with oversulfated chondroitin sulfate, cough syrup contaminated with diethylene glycol - these scandals didn't just cause outrage among consumers over the recent years. They have also served as a wake-up call for both suppliers and manufacturers in the pharmaceutical industry and have made apparent the need for companies on both sides to work together to exchange information.more
Dr. Karl Kolter of BASF Wins International Research Award
Dr. Karl Kolter, BASF head of Pharmaceutical Excipients Research and Development, was honored at the AAPS Annual Meeting and Exposition with the 2010 International Pharmaceutical Excipients Council Foundation (IPEC) Industry Research Achievement in Excipient Technology. Dr. Kolter received the newly established award in honor of his outstanding history of research into novel pharmaceutical excipients. more04.11.2010Celanese Advances Controlled-Release Science for the Pharmaceutical Industry
Celanese has announced that its subsidiary, Celanese EVA Performance Polymers, has launched VitalDose, a polymer-based excipient that facilitates drug makers' efforts to develop and commercialize novel controlled-release solutions. more
Securing Each Step
Like nearly all aspects of public and private business, healthcare management organizations and national governments are feeling price pressure, and many look to mitigate this by saving money when it comes to drugs. This pressure gets passed along the value chain to the manufacturers of excipients, who strive to provide the highest-quality products to their customers in a world where the regulatory framework is unclear. Brandi Schuster asked some of this year's CPhI exhibitors the following questions:more
Imagination Over Experience
Inventing The Future - The modern tablet development usually includes three basic formulation techniques - direct compression, dry compaction and wet granulation. Depending on the API, characteristics and the desired dosage, one of these formulation approaches is used. Direct compression is the most preferable method due to the low development costs, simple solvent free procedure and a much shorter time-to-market compared to the other methods. Disadvantages of this technique are powder flow difficulties, segregation, poor content uniformity and lubricant sensitivity. more
Adhering To Quality Demands
Take Responsibility - Quality of products is one of the most important parameters for global players, no matter in which branch, but when it comes to healthcare, it is definitely the most important of all. To ensure the highest standard in quality, it is inescapable to employ only the best experts on the market. Dr. Alen Guy is known as such an expert, working successfully in the excipients sector for several years. In May 2010 he joined IMCD Group one of the biggest distributors in the chemical industry, as technical director of pharmaceuticals. more
Hot Melt Extrusion Technology (HME)
Modern Manufacturing - HME has been on a successful path in the pharmaceutical industry for solubilization and bioavailability enhancement, particularly regarding poorly soluble drugs.HME Evolution
In other industries, such as plastic, rubber and food products, this technology has extensively been used since the1930s. About 20 years ago, the pharmaceutical industry began to employ melt extrusion as a promising solution for its solubilization of almost insoluble drugs. more15.06.2010
Turning Point
Sharp Focus - 2010 could be a watershed year for the excipient sector in Europe as amendments to the falsified medicines directive bring excipient quality and safety considerations to the fore. As the second decade in the 21st century gets underway, it is a pivotal time for excipient suppliers and users, with greater attention being paid than ever before to the quality and safety of materials used to manufacture pharmaceuticals. more- Legal
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