Underestimated Chemical Diversity

A Comprehensive Analysis of National and Regional Chemical Inventories

  • There are an ever-​greater number of industrial chemicals on the world market, but many lack publicly available information on aspects such as their chemical identities and hazard potential. © totojang1977/ShutterstockThere are an ever-​greater number of industrial chemicals on the world market, but many lack publicly available information on aspects such as their chemical identities and hazard potential. © totojang1977/Shutterstock

An international team of researchers has conducted a global review of all registered industrial chemicals: some 350,000 different substances are produced and traded around the world – well in excess of the 100,000 reached in previous estimates. For about a third of these substances, there is a lack of publicly accessible information.

The last time a list was compiled of all the chemicals available on the market and in circulation worldwide, it ran to 100,000 entries. Drawn up shortly after the turn of the millennium, the list focused on markets in the US, Canada and western Europe, which made sense because 20 years ago, these countries accounted for more than two thirds of worldwide chemical sales.

Global Market

Things have changed dramatically since then. First, turnover has more than doubled, reaching €3.4 billion in 2017; second, the global west now participates in just a third of the worldwide chemical trade, whereas China alone accounts for 37% of turnover. “We broadened our scope to take in the global market – and we’re now presenting a first comprehensive overview of all chemicals available worldwide,” says Zhanyun Wang, senior scientist at the Department of Civil, Environmental and Geomatic Engineering at ETH Zurich, Switzerland.

Working with a team of international experts, Wang brought together data from 22 registers covering 19 countries and regions (including the EU). The new list contains 350,000 entries. “The chemical diversity we know now is three times greater than 20 years ago,” says Wang. This, he says, is primarily because a larger number of registers are now taken into account: “As a result, our new list includes many chemicals that are registered in developing and transition countries – often under limited supervision.”

Confidential Business Information

On its own, this comprehensive list cannot provide information about which chemicals are hazardous to health or the environment, for example. “Our inventory is only the first step in the substances’ characterization,” says Wang, adding that previous work suggested that some 3% of all chemicals may give cause for concern.

If you apply this figure to the new multitude of chemicals, 6,000 new potentially problematic substances could be expected, he says.

Far more astonishing for Wang was the fact that a good third of all chemicals have inadequate descriptions in the various registers. About 70,000 entries are for mixtures and polymers (such as petroleum resin), with no details provided about the individual components. Another 50,000 entries relate to chemicals where the identities are considered confidential business information and are therefore not publicly accessible. “Only the manufacturers know what they are and how dangerous or toxic they are,” says Wang. “That leaves you with an uneasy feeling – like a meal where you’re told that it’s well cooked, but not what it contains.”

An Urgent Call for International Collaboration

Globalization and worldwide trade ensure that – unlike national registers – chemicals do not stop at national borders. As Wang and his colleagues note in their article in the journal Environmental Science & Technology, the various registers need therefore to be merged if we want to keep track of all the chemicals that are produced and traded anywhere in the world. “Only by joining forces, across different countries and disciplines, will we be able to cope with this ever-expanding chemical diversity,” says Wang.


The original publication by Zhanyun Wang et al. is available here.

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