„We Want to Be A Big Fish“
Siegfried CEO Wolfgang Wienand on the Company‘s Strategy and Future Growth Opportunities
Interview with Wolfgang Wienand, Siegfried

Small Substances with Big Effects
Trends and Drivers in API Development and Manufacturing
Thorsten Schüller, CHEManager

Expanding Expertise in Highly-Potent APIs
Siegfried Has Had to Reinvent and Fundamentally Change Itself Several Times
Thorsten Schüller, CHEManager

Every Drop Counts
At the German Site in Hameln, Siegfried Successfully Demonstrates Its Expertise in the Technologically Demanding Biologics Fill & Finish Segment. A Business with Future.
Thorsten Schüller, CHEManager

Sustainability — The Many Facets of Action
The Pharmaceutical and Biotech Industry Already Contributes Significantly to Reduce Its Environmental Footprint. Nevertheless, Even More Can Be Done.
Thorsten Schüller, CHEManager

Sustainability by Effective API Production
Siegfried Has Set Itself Ambitious Sustainability Targets. Significant Potential Is in Efficient Production Processes.
Thorsten Schüller, CHEManager

“Investments Always Pay Off”
CSO Jürgen Roos on Opportunities and Limits of Sustainability
Thorsten Schüller, CHEManager

This special issue of CHEManager International is dedicated to one of them: Siegfried. Once a fully integrated pharmaceutical company, Siegfried is one of the few suppliers today that can provide both the drug substance and the drug product development and production capabilities.

The journey of Siegfried began in 1873, when it was founded as a family company by pharmacist Samuel Benoni Siegfried in Zofingen, Switzerland – the city which, to this day, remains the company’s world headquarters. The original enterprise had only 12 employees; now, there are over 3,600 of them spread across the globe from the United States to Europe and China.

Despite the company's long history, it is primarily the developments of the last 14 years that have created the Siegfried we know today. Since 2010, sales have almost quadrupled, and the workforce has grown fivefold. Siegfried has expanded its technological base and geographic presence worldwide in recent years. In the process, the number of sites increased from three to 11.

In collaboration with the Swiss outsourcing partner for services and products along the pharmaceutical value chain (CDMO), we have compiled an issue to commemorate the extraordinary 150 year-long history and development of Siegfried. But as we appreciate our readers’ demand for independent, high-quality information we have tried to highlight the past and the present situation of Siegfried in the context of the respective market developments.

The focus of this issue, however, is not on Siegfried's history, but rather on the company's expertise and offerings today, its position in the CDMO market, and its strategic alignment for further growth.

Therefore, on the following pages you will not only read an insightful interview with Siegfried’s CEO, Wolfgang Wienand, on the company‘s presence and future vision. You will also find illuminating articles by our editorial staff about the prevailing trends in the chemical and pharmaceutical markets and about how the Swiss CDMO reacts and adapts to these trends in order to continue its success story.

You will read about the omnipresent trend of sustainability and how it challenges pharmaceutical companies and their suppliers and partners. You will also learn about the current trends in the areas of drug substance and drug product development and manufacturing.

This introductory overview provides the background against which we place Siegfried's current activities – e.g., the development of innovative and increasingly sustainable production processes – in the context of current market events.

And a graphic timeline provides you with an overview of Siegfried's impressive company history based on important milestones in the company's development (> PDF Download).

150 years of company history are proof of the fact that Siegfried has been able to withstand market disruptions and adapt to changing business conditions by not only being resilient and persistent but, first and foremost, being innovative and courageous. These characteristics and qualities are in demand even more today than 150 years ago. Business challenges have probably never been more numerous and serious than today; therefore, companies cannot stand still. They need to be on the move constantly.

You can download the complete special issue as a PDF (or read the e-paper) or access the individual articles via the links below.

With this, we wish you an insightful reading.

Michael Reubold und Ralf Kempf, CHEManager